This handbook provides a comprehensive overview of Islamic ethical issues within a wide spectrum of philosophy of science topics, examining the development of the model of moral inclusiveness in economics, science and society from ontological, epistemological and analytical perspectives. This paradigm takes the view that ethics is systemically endogenous, and can be studied by the most rigorous scientific analysis pertaining to diverse issues and problems of ethicality in socio-scientific inquiry. This book takes a sweeping multidisciplinary approach that is deeply phenomenological, to the nature and logic of scientific inquiry of, and in, the Qur’an. Such an approach invokes the episteme of the unity of knowledge in the socio-scientific systemic sense. The book’s respective sections focus on the nature, logic and role that ethics plays in formulating new vistas of alternative epistemic futures in Islamic economics, finance, and the social sciences. It is situated within the broader context of the pandemic, and the post-Covid-19 era, aimed at conceptualising a distinctive new outlook of existence in Islamic philosophy. The content is rigorously conceptual, qualitative, quantitative and applied. Covering a diversity of subject areas from philosophy of science, to economics and sociology within the realm of Islamic philosophy, this is a key text for scholars in these respective arenas, led by pioneering scholar in Islamic studies.