Age-related bone loss resulting in fracture is a major public health issue. DXA is the gold standard tool to examine bone mineral density and diagnose osteoporosis as recommended by the WHO. This case-based book covers broad topics in clinical application of DXA, ranging from selection of the region of interest in spine and hip, diagnosis of BMD using T- or Z-score, to the interpretation of follow-up DXA studies and pitfalls which are not listed in the 2019 ISCD guideline. Last chapter includes some cases for readers to inspect their ability in interpreting DXA studies and making a correct diagnosis. It will be a valuable reference for clinicians and radiologists to achieve accurate interpretation and reporting DXA studies with confidence via case exercises.