Physical Earthquake Forecasting and Prediction: T-TECTO Omega System covers recent research on earthquake physics, such as the Cosserat continuum theory of faulting and earthquakes, global tectonic stress field, chaotic synchronizations in earthquakes, and slow solitary tectonic waves in the Earth’s crust. Based on new advances in these fields, the operational earthquake forecasting system called T-TECTO Omega System has been developed. The author’s previous book, The Omega-Theory: A New Physics of Earthquakes, explored an important breakthrough in earthquake physics, the Omega-Theory. This new book is dedicated to statistically evaluating that theory and the models based on it. The text is divided into five parts: statistical testing of the physical earthquake predictions, tectonic stress, time-synchronizations, tectonic couple-stress, and alert system and operational earthquake forecasting and prediction. The book’s final part also covers some of the challenges of operational earthquake forecasting, its political and social implications, limits, and problems. This book is essential reading for those interested in the cutting-edge of earthquake forecasting and prediction.