Alginate Biomaterial: Drug Delivery Strategies and Biomedical Engineering

This book focuses on recent trends of research on alginate-based biomaterials in Drug Delivery strategies and biomedical engineering. It contains the widely used alginate-based biomaterials as micro to nano-controlled drug delivery (oral, ocular delivery, topical delivery, etc.) and its fabrication technology, characterization, and biomedical aspects (such as cancer therapy, tissue engineering, gene delivery, vaccine delivery, enzyme immobilization, wound healing, dental applications, etc.) in a single book. The chapters cover updated information, current research trends, informatics, and all aspects of applications.

Alginate is a U.S. Food and Drug Administration (FDA)-approved natural biomaterial and has diverse biomedical applications. In recent years, researchers and scientists are working on the alginate-based drug delivery systems that have been designed and characterized as a matrix, micro to nanocarriers, fibers, composite/scaffolds, etc. Alginate hasversatile properties such as biodegradable, biocompatible, nontoxic, and easily available. This book especially highlights both the drug delivery strategies and biomedical engineering aspects such as controlled drug delivery, drug targeting to the site of action, cancer therapy, gene and vaccine delivery, enzyme immobilization, tissue engineering, and regenerative medicine.

Sougata Jana has completed his Ph.D. in pharmaceutical technology at Maulana Abul Kalam Azad University of Technology (MAKAUT), West Bengal., India. He has spent 14 years in pharmacy, including teaching, research, and health services. Sougata has published over 30 research and review articles in different national and international peer-reviewed journals. He has also edited 12 books and published more than 45 book chapters in edited books published by internationally renowned publishers. He is a reviewer for peer-reviewed international journals. Sougata is a life member of the Association of Pharmaceutical Teachers of India (APTI) and holds an associateship with the Institution of Chemists (AIC), India. He successfully guided 17 postgraduate students in their research projects. Sougata is working on drug delivery science and technology, including modification of synthetic and natural biopolymers, microparticles, nanoparticles, and semisolids and an interpenetrating network (IPN) system for controlled drug delivery. Subrata Jana is a Professor in the Department of Chemistry, Indira Gandhi National Tribal University (Central University), Amarkantak, Madhya Pradesh, India. His current research focuses on the design and synthesis of artificial receptors for the recognition of anions, cations, and biomolecules along with biodegradable polymeric-based carrier systems for the delivery of drug molecules. So far, he has published around 40 research papers in peer-reviewed international journals and contributed more than 20 book chapters in edited books. Subrata obtained his Ph.D. in organic chemistry from the Indian Institute of Engineering Science and Technology (IIEST), Shibpur, India. Then he worked with Professor (Dr.) Fraser Hof at the University of Victoria, Canada, and Dr. Kenneth J. Woycechowsky at the University of Utah, USA, as a postdoc. Overall, he has extensively studied the supramolecular behavior of the host-guest interaction and synthesis of different heterocyclic moieties.