Nano Physical Pharmaceutics

Nanomedicine is an emerging and rapidly evolving field, which could significantly help in early disease diagnosis, therapeutic improvement, novel therapeutic modality development, and medical expenditure reduction. The challenge remains, however, that the specially designed and carefully synthesized nanomedicines function poorly in animal verification despite great performance in vitro. A deeper understanding of the physicochemical properties of nanomedicine is the key.

This book applies physical theories and models to determine the parameters for controlling the physicochemical properties of nanomedicines, including micelles, liposomes, and inorganic nanoparticles. Qualitative and quantitative relationships are established to provide guidance for nanomedicine design, characterization, and analysis. The text also compiles cutting-edge research in nanomedicine from the interdisciplinary team of the Department of Nanomedicine at Naval Medical University, China, which is currently establishing the characteristic discipline called Nano Physical Pharmaceutics. Edited by Wei Li, a prominent nanotechnology researcher, this book will appeal to anyone involved in nanotechnology, medicine, macromolecular science, biology, chemistry, and especially those with an interest in drug delivery or cancer therapy.

Wei Li is professor at Naval Medical University (NMU), China, and director of the Department of Nanomedicine and principal investigator at Shanghai Key Laboratory of Cell Engineering, NMU. He also started a new nanomedical lab at NMU under a special talent program. Dr Li has published over 73 peer-reviewed papers, is chief editor of Nano Physical Pharmaceutics, has created a series of key parameters and qualitative as well as quantitative relationships, and has independently designed five sets of equipment for the translation of nanomedicine, with several products in the trial stage and two formulations successfully translated to application. His research focuses on nano physical pharmaceutics, fine nanocarrier engineering, and nanoimmunotherapy.