The results of the research allowed to justify a set of hygienic measures aimed at the necessity of priority introduction of the system of social and hygienic monitoring of quality indicators of tap and pre-treated drinking water, to establish their impact on the health status of rural residents; to recommend the introduction of installations for additional treatment of drinking water in the first place in those rural taxa, whose residents do not have access to quality drinking water; to carry out a comparative assessment of quality indicators of tap and pre-treated drinking water. It was found that the majority of rural residents in certain taxa of Dnipropetrovsk region have coverage rates of collective water supply systems 18.5-1.5 times lower than the recommended "National Target Indicators of Ukraine" in 2015, and 34, 6% of rural residents do not have a centralized wastewater disposal system.